منابع مشابه
Execution of RIPK3-regulated necrosis
Necroptosis is a form of regulated necrotic cell death that is mediated by receptor-interacting protein 1 (RIP1) and RIP3 kinases. Diverse receptors, including death receptors, Toll-like receptors, interferon receptors, and DAI DNA receptors are able to trigger necroptosis. The newly identified MLKL protein functions downstream of RIP1/RIP3 and is essential for the execution of necroptosis. Stu...
متن کاملBack to the roots of regulated necrosis
In recent years, our knowledge of how cells die by regulated pathways of necrosis has increased tremendously. In this issue, Distéfano et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605110) provide yet another milestone in our understanding of regulated necrosis as they identify a ferroptosis-like cell death in Arabidopsis thaliana.
متن کاملPyroptosis as a Regulated Form of Necrosis
Pyroptosis is characterized by pore formation in the plasma membrane, cell swelling, and membrane disruption. These cellular events are also noted in necrosis, but not apoptosis, which is defined as a mode of regulated or programmed necrosis. Jorgensen et al have defined pyroptosis by the following 4 criteria: (1) programmed by an inflammatory caspase activation, (2) pore formation in the plasm...
متن کاملPyroptosis as a Regulated Form of Necrosis
Pyroptosis is characterized by pore formation in the plasma membrane, cell swelling, and membrane disruption. These cellular events are also noted in necrosis, but not apoptosis, which is defined as a mode of regulated or programmed necrosis. Jorgensen et al have defined pyroptosis by the following 4 criteria: (1) programmed by an inflammatory caspase activation, (2) pore formation in the plasm...
متن کاملPyroptosis as a Regulated Form of Necrosis
Pyroptosis is characterized by pore formation in the plasma membrane, cell swelling, and membrane disruption. These cellular events are also noted in necrosis, but not apoptosis, which is defined as a mode of regulated or programmed necrosis. Jorgensen et al have defined pyroptosis by the following 4 criteria: (1) programmed by an inflammatory caspase activation, (2) pore formation in the plasm...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Reactome - a curated knowledgebase of biological pathways
سال: 2015
ISSN: 1934-1792
DOI: 10.3180/react_355207.1